[Fluorescence and HTS
[Cell Assays, Pharmacol.
[Immunochem., Liposomes
[Membrane Biophysics
[Chemical Physics of Water] 

 These publications center on biosensors, primarily those based on the light-addressable potentiometric sensor (LAPS):

Parce, J.W., Owicki, J.C., Kercso, K.M., Sigal, G.B., Wada, H.G., Muir, V.C., Bousse, L.J., Ross, K.L., Sikic, B.I., & McConnell, H.M. (1989) Detection of Cell-Affecting Agents with a Silicon Biosensor.  Science 246:243-247.

Bousse, L.J., Parce, J.W., Owicki, J.C., & Kercso, K.M. (1990) Silicon Micromachining in the Fabrication of Biosensors using Living Cells.  Technical Digest IEEE Solid State Sensor and Actuator Workshop, pp. 173-176.

Parce, J.W., Sigal, G.B., Kercso, K.M., & Owicki, J.C. (1990) The Silicon Microphysiometer:  Detection of Biological Effects of Chemical and Biochemical Agents by Alterations of Cellular Metabolic Rate.  In: Biosensor Technology, Fundamentals and Applications, Buck, R.P., Hatfield, W.E., Umana, M., and Bowden, E.F. (eds.), Marcel Dekker, Inc., New York, NY.

Parce, J.W., Owicki, J.C., & Kercso, K.M. (1990) Biosensors for Directly Measuring Cell-Affecting Agents.  Annales de Biologie Clinique 48:639-641.

Owicki, J.C., & Parce, J.W. (1990) Bioassays with a Microphysiometer.  Nature 344:271-272 (invited product review).

McConnell, H.M., Rice, P., Wada, H.G., Owicki, J.C., & Parce, J.W. (1991) The Microphysiometer Biosensor.  Curr. Opinion Struct. Biol. 1:647-652.

Bousse, L.J., Miller, D.L., Owicki,  J.C., & Parce, J.W. (1991) Rapid Determination of Cellular Metabolic Rates with a Silicon Microphysiometer. Technical Digest Transducers 91, 7477, San Francisco, June 1991.

Bousse, L., Owicki, J.C.,  and Parce, J.W. (1992) Biosensors with Microvolume Reaction Chambers.  pp. 145-166 In: Chemical Sensor Technology, Vol. 4 (Yamauchi, S.,  Ed.), Kodansha, Tokyo, and Elsevier, Amsterdam.

McConnell, H.M., Owicki, J.C., Parce, J.W., Miller, D.L., Baxter, G.T., Wada, H.G., & Pitchford, S. (1992) The Cytosensor Microphysiometer:  Biological Applications of Silicon Technology.  Science 257:1906-1912.

Baxter, G.T., Bousse, L.J., Dawes, T.D., Libby, J.M., Modlin, D.N., Owicki, J.C., & Parce, J.W.  (1994)  Microfabrication in Silicon Microphysiometry.  Clin. Chem. 40:1800-1804.

Owicki, J.C., Bousse, L.J., Hafeman, D.G., Kirk, G.L., Olson, J.D., Wada, H.G., & Parce, J.W. (1994) The Light-Addressable Potentiometric Sensor:  Principles and Biological Applications.  Ann. Rev. Biophys. Biomolec. Struct. 23:87-113.

Alajoki, M.L., Baxter, G.T., Bemiss, W.R., Blau, D., Bousse, L.J., Chan, S.D.H., Dawes, T.D., Hahnenberger, K.M., Hamilton, J.M., Lam, P., McReynolds, R.J., Modlin, D.M., Owicki, J.C., Parce, J.W., Redington, D., Stevenson, K., Wada, H.G., & Williams, J. (1997) High-Performance Microphysiometry in Drug Discovery.   In: High-Throughput Screening (Ed. J. Devlin, Dekker, NY), Chapt. 25, invited chapter.

Parak, W.J., Hofmann, U.G., Gaub, H.E., & Owicki, J.C. (1997)  Lateral resolution of LAPS devices:  Theoretical and experimental investigations.  Sensors and Actuators, A 63:47-57.


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